Sources

All 404 sources cited on this site, grouped by type in the order of our sourcing hierarchy. Every citation on every page resolves to one of these entries.

Last updated October 17, 2026

FDA drug label

Naltrexone hydrochloride tablets USP, 50 mg — prescribing information (SpecGx LLC; DailyMed SPL version 15). SpecGx LLC, via DailyMed (U.S. National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Does Naltrexone Work?, How Long Does Naltrexone Stay in Your System?, How Long Does Naltrexone Take to Work?, Is Naltrexone a Controlled Substance?, Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo, Medication to Stop Drinking, Nalmefene, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone and Bupropion (Contrave), Naltrexone Brand Names, How Much Does Naltrexone Cost?, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Can You Take Naltrexone While Pregnant?, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Disulfiram (Antabuse), Naltrexone vs Naloxone: What's the Difference?, Naltrexone vs Suboxone, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Precipitated Withdrawal, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, The Sinclair Method: What It Is and What the Evidence Shows, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help, What to Avoid When Taking Low-Dose Naltrexone (LDN), What to Avoid When Taking Naltrexone, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Vivitrol (naltrexone for extended-release injectable suspension) — prescribing information (DailyMed SPL version 39). Alkermes, Inc., via DailyMed (U.S. National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Does Naltrexone Work?, How Long Does Naltrexone Stay in Your System?, How Long Does Naltrexone Take to Work?, Is Naltrexone a Controlled Substance?, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Brand Names, How Much Does Naltrexone Cost?, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone Implant, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Can You Take Naltrexone While Pregnant?, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Disulfiram (Antabuse), Naltrexone vs Naloxone: What's the Difference?, Naltrexone vs Suboxone, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Precipitated Withdrawal, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help, What to Avoid When Taking Naltrexone, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Naltrexone for extended-release injectable suspension (kit) — prescribing information (unbranded; DailyMed SPL version 1). Amneal Pharmaceuticals LLC (distributor; manufactured by Alkermes, Inc.), via DailyMed, 2026. Accessed 2026-10-17.Note: Sold under Vivitrol's NDA 021897 without the brand name. We could not verify a price or current availability.Cited on: Naltrexone: What It Is Used For and How It Works, Naltrexone Brand Names, How Much Does Naltrexone Cost?, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help
Acamprosate calcium delayed-release tablets — prescribing information (Glenmark; DailyMed SPL version 12). Glenmark Pharmaceuticals Inc., USA, via DailyMed, 2026. Accessed 2026-10-17.Cited on: Medication to Stop Drinking, How Much Does Naltrexone Cost?, Naltrexone vs Acamprosate: Which Works Better?, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Naloxone hydrochloride injection, USP — prescribing information (Hospira; DailyMed SPL version 35). Hospira, Inc., via DailyMed, 2023. Accessed 2026-10-17.Cited on: Naltrexone vs Naloxone: What's the Difference?, Precipitated Withdrawal
Narcan (naloxone hydrochloride) nasal spray 4 mg — Drug Facts label, over the counter (DailyMed SPL version 4). Emergent Devices Inc., via DailyMed, 2026. Accessed 2026-10-17.Cited on: Nalmefene, Naltrexone Brand Names, Naltrexone Implant, Naltrexone vs Naloxone: What's the Difference?, Precipitated Withdrawal
Contrave (naltrexone hydrochloride and bupropion hydrochloride) extended-release tablets. Nalpropion Pharmaceuticals LLC, via DailyMed (U.S. National Library of Medicine), 2025. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Does Naltrexone Work?, How Long Does Naltrexone Take to Work?, Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone and Bupropion (Contrave), Naltrexone Brand Names, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, What to Avoid When Taking Low-Dose Naltrexone (LDN), What to Avoid When Taking Naltrexone
Vivitrol (naltrexone for extended-release injectable suspension). Alkermes, Inc., via Drugs@FDA (US Food and Drug Administration), 2010. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help
ReVia (naltrexone hydrochloride tablets USP), 50 mg. Duramed Pharmaceuticals, Inc., via Drugs@FDA (US Food and Drug Administration), 2013. Accessed 2026-10-17.Cited on: Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor
Disulfiram tablets USP, 250 mg. Alvogen, Inc., via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Medication to Stop Drinking, Naltrexone vs Disulfiram (Antabuse)
Topamax (topiramate) tablets and capsules. Janssen Pharmaceuticals, Inc., via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Neurontin (gabapentin) capsules, tablets and oral solution. Viatris Specialty LLC, via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Ozempic (semaglutide) injection. Novo Nordisk, via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Opvee (nalmefene hydrochloride) nasal spray. Indivior Inc., via DailyMed (U.S. National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Nalmefene, Precipitated Withdrawal
Zurnai (nalmefene hydrochloride) injection, auto-injector. Knoa Pharma LLC, via DailyMed (U.S. National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Nalmefene, Precipitated Withdrawal
Nalmefene hydrochloride injection. Knoa Pharma LLC, via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Nalmefene
Wellbutrin XL (bupropion hydrochloride extended-release) tablets. Bausch Health US LLC, via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Embeda (morphine sulfate and naltrexone hydrochloride) extended-release capsules. US Food and Drug Administration, n.d.. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
Troxyca ER (oxycodone hydrochloride and naltrexone hydrochloride) extended-release capsules. US Food and Drug Administration, n.d.. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
Vivitrol (naltrexone for extended-release injectable suspension). US Food and Drug Administration, n.d.. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Suboxone (buprenorphine and naloxone) sublingual film, CIII. Indivior Inc., via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Naltrexone vs Suboxone, Precipitated Withdrawal
Imodium (loperamide hydrochloride) capsules. US Food and Drug Administration, n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Low-Dose Naltrexone (LDN), What to Avoid When Taking Naltrexone
ProvayBlue (methylene blue) injection. American Regent, Inc., via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Low-Dose Naltrexone (LDN)
Auvelity (dextromethorphan hydrobromide and bupropion hydrochloride) extended-release tablets. Axsome Therapeutics, Inc., via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Low-Dose Naltrexone (LDN)
Tylenol Extra Strength (acetaminophen) caplets. Kenvue Brands LLC, via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Advil (ibuprofen) liquid-filled capsules. Haleon US Holdings LLC, via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Lomotil (diphenoxylate hydrochloride and atropine sulfate) tablets. Pfizer Laboratories Div Pfizer Inc., via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Xanax (alprazolam) tablets. Viatris Specialty LLC, via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Thioridazine hydrochloride tablets USP. Mylan Pharmaceuticals Inc., via DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone

Clinical guideline

American Psychiatric Association. The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder. American Psychiatric Association Publishing, 2018. DOI: 10.1176/appi.books.9781615371969. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Can You Take Naltrexone While Pregnant?, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Disulfiram (Antabuse), Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, The Sinclair Method: What It Is and What the Evidence Shows
US Department of Veterans Affairs; US Department of Defense. VA/DoD Clinical Practice Guideline for the Management of Substance Use Disorders, version 5.0. U.S. Department of Veterans Affairs, 2021. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Does Naltrexone Work?, How Long Does Naltrexone Take to Work?, Medication to Stop Drinking, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Disulfiram (Antabuse), Naltrexone vs Suboxone, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, The Sinclair Method: What It Is and What the Evidence Shows, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Nalmefene for reducing alcohol consumption in people with alcohol dependence (technology appraisal guidance TA325). National Institute for Health and Care Excellence (NICE), 2014. Accessed 2026-10-17.Note: UK guidance on nalmefene, a different medicine. It is not guidance on naltrexone or the Sinclair Method.Cited on: Nalmefene, The Sinclair Method: What It Is and What the Evidence Shows
Reus VI, Fochtmann LJ, Bukstein O, et al.. The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder. American Journal of Psychiatry 2018;175(1):86–90. DOI: 10.1176/appi.ajp.2017.1750101. PMID: 29301420. Accessed 2026-10-17.Cited on: Naltrexone for Alcohol Use Disorder, Naltrexone vs Acamprosate: Which Works Better?
Alcohol-Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking (High-Risk Drinking) and Alcohol Dependence. National Institute for Health and Care Excellence (NICE), 2014. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, How Long Does Naltrexone Take to Work?, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Disulfiram (Antabuse)
Prescribing Pharmacotherapies for Patients With Alcohol Use Disorder. Substance Abuse and Mental Health Services Administration, 2021. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, How Long Does Naltrexone Stay in Your System?, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Naltrexone vs Acamprosate: Which Works Better?, What to Avoid When Taking Naltrexone
Medications for Opioid Use Disorder. Substance Abuse and Mental Health Services Administration, 2021. Accessed 2026-10-17.Cited on: Naltrexone: What It Is Used For and How It Works, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Can You Take Naltrexone While Pregnant?, Naltrexone vs Suboxone, Precipitated Withdrawal, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Crabb DW, Im GY, Szabo G, Mellinger JL, Lucey MR. Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases. Hepatology 2020;71(1):306-333. DOI: 10.1002/hep.30866. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Jophlin LL, Singal AK, Bataller R, et al. ACG clinical guideline: alcohol-associated liver disease. Am J Gastroenterol 2024;119(1):30-54. DOI: 10.14309/ajg.0000000000002572. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Weimer MB, Herring AA, Kawasaki SS, Meyer M, Kleykamp BA, Ramsey KS. ASAM clinical considerations: buprenorphine treatment of opioid use disorder for individuals using high-potency synthetic opioids. J Addict Med 2023;17(6):632-639. DOI: 10.1097/ADM.0000000000001202. Accessed 2026-10-17.Cited on: Precipitated Withdrawal
Arab JP, Malhi H, Winder GS, Fontana RJ. AGA clinical practice update on the evaluation and management of metabolic dysfunction- and alcohol-associated liver disease: expert review. Clin Gastroenterol Hepatol. Published online September 22, 2026. DOI: 10.1016/j.cgh.2026.07.027. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG. AUDIT: the Alcohol Use Disorders Identification Test: guidelines for use in primary health care, second edition. World Health Organization, 2001. Accessed 2026-10-17.

Systematic review / meta-analysis

McPheeters M, O'Connor EA, Riley S, et al.. Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (Comparative Effectiveness Review No. 262) — Executive Summary. Agency for Healthcare Research and Quality (AHRQ), 2023. DOI: 10.23970/AHRQEPCCER262. Accessed 2026-10-17.Cited on: Medication to Stop Drinking, Naltrexone for Alcohol Use Disorder, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Disulfiram (Antabuse), Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Rösner S, Hackl-Herrwerth A, Leucht S, Vecchi S, Srisurapanont M, Soyka M. Opioid antagonists for alcohol dependence. Cochrane Database of Systematic Reviews 2010;(12):CD001867. DOI: 10.1002/14651858.CD001867.pub3. PMID: 21154349. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Does Naltrexone Work?, Naltrexone: What It Is Used For and How It Works, Naltrexone for Alcohol Use Disorder, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, The Sinclair Method: What It Is and What the Evidence Shows
Maisel NC, Blodgett JC, Wilbourne PL, Humphreys K, Finney JW. Meta-analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?. Addiction 2013;108(2):275–293. DOI: 10.1111/j.1360-0443.2012.04054.x. PMID: 23075288. Accessed 2026-10-17.Note: Compares each drug's effect versus placebo across trials (an indirect comparison), not head-to-head trials.Cited on: Naltrexone for Alcohol Use Disorder, Naltrexone vs Acamprosate: Which Works Better?
Jonas DE, Amick HR, Feltner C, et al.. Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis. JAMA 2014;311(18):1889–1900. DOI: 10.1001/jama.2014.3628. PMID: 24825644. Accessed 2026-10-17.Cited on: Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
McPheeters M, O'Connor EA, Riley S, et al.. Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis. JAMA 2023;330(17):1653–1665. DOI: 10.1001/jama.2023.19761. PMID: 37934220. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone for Alcohol Use Disorder, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, The Sinclair Method: What It Is and What the Evidence Shows, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Rösner S, Hackl-Herrwerth A, Leucht S, Lehert P, Vecchi S, Soyka M. Acamprosate for alcohol dependence. Cochrane Database of Systematic Reviews 2010;(9):CD004332. DOI: 10.1002/14651858.CD004332.pub2. PMID: 20824837. Accessed 2026-10-17.Cited on: Naltrexone vs Acamprosate: Which Works Better?
Minozzi S, La Rosa GRM, Salis F, et al.. Combined pharmacological and psychosocial interventions for alcohol use disorder. Cochrane Database of Systematic Reviews 2025;3(3):CD015673. DOI: 10.1002/14651858.CD015673.pub2. PMID: 40110869. Accessed 2026-10-17.Cited on: Naltrexone for Alcohol Use Disorder, Naltrexone vs Acamprosate: Which Works Better?
Palpacuer C, Duprez R, Huneau A, et al.. Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders: a systematic review with direct and network meta-analyses on nalmefene, naltrexone, acamprosate, baclofen and topiramate. Addiction 2018;113(2):220–237. DOI: 10.1111/add.13974. PMID: 28940866. Accessed 2026-10-17.Cited on: Nalmefene, The Sinclair Method: What It Is and What the Evidence Shows
Mann K, Torup L, Sørensen P, et al.. Nalmefene for the management of alcohol dependence: review on its pharmacology, mechanism of action and meta-analysis on its clinical efficacy. European Neuropsychopharmacology 2016;26(12):1941–1949. DOI: 10.1016/j.euroneuro.2016.10.008. PMID: 27842940. Accessed 2026-10-17.Cited on: Nalmefene, The Sinclair Method: What It Is and What the Evidence Shows
Elmosalamy A, Sirohi A, Moustafa A, et al.. Extended-release naltrexone versus oral naltrexone for substance use disorders: A systematic review and meta-analysis. Drug and Alcohol Dependence 2025;274:112789. DOI: 10.1016/j.drugalcdep.2025.112789. PMID: 40660643. Accessed 2026-10-17.Cited on: Naltrexone for Alcohol Use Disorder, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Minozzi S, Amato L, Vecchi S, Davoli M, Kirchmayer U, Verster A. Oral naltrexone maintenance treatment for opioid dependence. Cochrane Database Syst Rev 2011;(4):CD001333. DOI: 10.1002/14651858.CD001333.pub4. PMID: 21491383. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Naltrexone: What It Is Used For and How It Works, Naltrexone vs Suboxone
Garbutt JC, Greenblatt AM, West SL, et al. Clinical and biological moderators of response to naltrexone in alcohol dependence: a systematic review of the evidence. Addiction 2014;109(8):1274–1284. DOI: 10.1111/add.12557. PMID: 24661324. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Naltrexone for Alcohol Use Disorder
Hartwell EE, Feinn R, Morris PE, et al. Systematic review and meta-analysis of the moderating effect of rs1799971 in OPRM1, the mu-opioid receptor gene, on response to naltrexone treatment of alcohol use disorder. Addiction 2020;115(8):1426–1437. DOI: 10.1111/add.14975. PMID: 31961981. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Naltrexone for Alcohol Use Disorder
Bolton M, Hodkinson A, Boda S, et al. Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a systematic review and meta-analysis. BMC Med 2019;17(1):10. DOI: 10.1186/s12916-018-1242-0. PMID: 30642329. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor
Parker CE, Nguyen TM, Segal D, MacDonald JK, Chande N. Low dose naltrexone for induction of remission in Crohn's disease. Cochrane Database Syst Rev 2018;4(4):CD010410. DOI: 10.1002/14651858.CD010410.pub3. PMID: 29607497. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label
Byambasuren O, Atkins T, Baptista S, Glasziou P, Chakraborty S. Effect of low-dose naltrexone for long COVID: a systematic review and meta-analysis. BMJ Open 2026;16(7):e111253. DOI: 10.1136/bmjopen-2025-111253. PMID: 42463201. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Vatvani AD, Patel P, Hariyanto TI, Yanto TA. Efficacy and safety of low-dose naltrexone for the management of fibromyalgia: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis. Korean J Pain 2024;37(4):367–378. DOI: 10.3344/kjp.24202. PMID: 39344363. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor
Hegde NC, Mishra A, V D, Maiti R, Hota D, Srinivasan A. Low dose naltrexone in the management of chronic pain syndrome: a meta-analysis of randomized controlled clinical trials. Curr Pain Headache Rep 2025;29(1):96. DOI: 10.1007/s11916-025-01411-1. PMID: 40540205. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor
Ray LA, Green R, Roche DJO, Magill M, Bujarski S. Naltrexone effects on subjective responses to alcohol in the human laboratory: a systematic review and meta-analysis. Addict Biol 2019;24(6):1138–1152. DOI: 10.1111/adb.12747. PMID: 31148304. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor
Hendershot CS, Wardell JD, Samokhvalov AV, Rehm J. Effects of naltrexone on alcohol self-administration and craving: meta-analysis of human laboratory studies. Addict Biol 2017;22(6):1515–1527. DOI: 10.1111/adb.12425. PMID: 27411969. Accessed 2026-10-17.Cited on: Naltrexone and Alcohol: What Happens If You Drink on It
Panin F, Peana AT. Sleep and the pharmacotherapy of alcohol use disorder: unfortunate bedfellows. A systematic review with meta-analysis. Front Pharmacol 2019;10:1164. DOI: 10.3389/fphar.2019.01164. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?
Hariyanto TI, Vatvani AD, Patel P, Yanto TA. Corrigendum: Efficacy and safety of low-dose naltrexone for the management of fibromyalgia: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis. Korean J Pain 2026;39(1):147-149. DOI: 10.3344/kjp.25393. Accessed 2026-10-17.Cited on: LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo
Skinner MD, Lahmek P, Pham H, Aubin HJ. Disulfiram efficacy in the treatment of alcohol dependence: a meta-analysis. PLoS One 2014;9(2):e87366. DOI: 10.1371/journal.pone.0087366. Accessed 2026-10-17.Cited on: Medication to Stop Drinking, Naltrexone vs Disulfiram (Antabuse)
Agabio R, Saulle R, Rösner S, Minozzi S. Baclofen for alcohol use disorder. Cochrane Database Syst Rev 2023;1(1):CD012557. DOI: 10.1002/14651858.CD012557.pub3. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Larney S, Gowing L, Mattick RP, Farrell M, Hall W, Degenhardt L. A systematic review and meta-analysis of naltrexone implants for the treatment of opioid dependence. Drug Alcohol Rev 2014;33(2):115-128. DOI: 10.1111/dar.12095. Accessed 2026-10-17.Cited on: Naltrexone Implant
Atluru S, Bruehlman AK, Vaughn P, Schauberger CW, Smid MC. Naltrexone compared with buprenorphine or methadone in pregnancy: a systematic review. Obstet Gynecol 2024;143(3):403-410. DOI: 10.1097/AOG.0000000000005510. Accessed 2026-10-17.Cited on: Can You Take Naltrexone While Pregnant?
Gregory C, Yadav K, Linders J, Sikora L, Eagles D. Incidence of buprenorphine-precipitated opioid withdrawal in adults with opioid use disorder: a systematic review. Addiction 2025;120(1):7-20. DOI: 10.1111/add.16646. Accessed 2026-10-17.Cited on: Precipitated Withdrawal
Kornør H, Lobmaier PPK, Kunøe N. Sustained-release naltrexone for opioid dependence. Cochrane Database Syst Rev 2025;5(5):CD006140. DOI: 10.1002/14651858.CD006140.pub3. Accessed 2026-10-17.Cited on: Naltrexone Implant
Jørgensen CH, Pedersen B, Tønnesen H. The efficacy of disulfiram for the treatment of alcohol use disorder. Alcohol Clin Exp Res 2011;35(10):1749-1758. DOI: 10.1111/j.1530-0277.2011.01523.x. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse)

Randomized controlled trial

Heinälä P, Alho H, Kiianmaa K, Lönnqvist J, Kuoppasalmi K, Sinclair JD. Targeted use of naltrexone without prior detoxification in the treatment of alcohol dependence: a factorial double-blind, placebo-controlled trial. Journal of Clinical Psychopharmacology 2001;21(3):287–292. DOI: 10.1097/00004714-200106000-00006. PMID: 11386491. Accessed 2026-10-17.Cited on: Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, The Sinclair Method: What It Is and What the Evidence Shows
Anton RF, O'Malley SS, Ciraulo DA, et al.. Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA 2006;295(17):2003–2017. DOI: 10.1001/jama.295.17.2003. PMID: 16670409. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Does Naltrexone Work?, Medication to Stop Drinking, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone vs Acamprosate: Which Works Better?, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Kranzler HR, Armeli S, Tennen H, et al.. Targeted naltrexone for early problem drinkers. Journal of Clinical Psychopharmacology 2003;23(3):294–304. DOI: 10.1097/01.jcp.0000084030.22282.6d. PMID: 12826991. Accessed 2026-10-17.Cited on: Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, The Sinclair Method: What It Is and What the Evidence Shows
Hernandez-Avila CA, Song C, Kuo L, Tennen H, Armeli S, Kranzler HR. Targeted versus daily naltrexone: secondary analysis of effects on average daily drinking. Alcoholism: Clinical and Experimental Research 2006;30(5):860–865. DOI: 10.1111/j.1530-0277.2006.00101.x. PMID: 16634855. Accessed 2026-10-17.Cited on: The Sinclair Method: What It Is and What the Evidence Shows
Kranzler HR, Tennen H, Armeli S, et al.. Targeted naltrexone for problem drinkers. Journal of Clinical Psychopharmacology 2009;29(4):350–357. DOI: 10.1097/JCP.0b013e3181ac5213. PMID: 19593174. Accessed 2026-10-17.Cited on: Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, The Sinclair Method: What It Is and What the Evidence Shows
Santos GM, Ikeda J, Coffin P, et al.. Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial. American Journal of Psychiatry 2022;179(12):915–926. DOI: 10.1176/appi.ajp.20220335. PMID: 36285404. Accessed 2026-10-17.Cited on: Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, The Sinclair Method: What It Is and What the Evidence Shows
Laaksonen E, Koski-Jännes A, Salaspuro M, Ahtinen H, Alho H. A randomized, multicentre, open-label, comparative trial of disulfiram, naltrexone and acamprosate in the treatment of alcohol dependence. Alcohol and Alcoholism 2008;43(1):53–61. DOI: 10.1093/alcalc/agm136. PMID: 17965444. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse), The Sinclair Method: What It Is and What the Evidence Shows
Garbutt JC, Kranzler HR, O'Malley SS, et al.. Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial. JAMA 2005;293(13):1617–1625. DOI: 10.1001/jama.293.13.1617. PMID: 15811981. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, How Long Does Naltrexone Take to Work?, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help
Sullivan MA, Bisaga A, Pavlicova M, et al.. A Randomized Trial Comparing Extended-Release Injectable Suspension and Oral Naltrexone, Both Combined With Behavioral Therapy, for the Treatment of Opioid Use Disorder. American Journal of Psychiatry 2019;176(2):129–137. DOI: 10.1176/appi.ajp.2018.17070732. PMID: 30336703. Accessed 2026-10-17.Cited on: Naltrexone vs Vivitrol: Pill or Monthly Shot?
Volpicelli JR, Rhines KC, Rhines JS, Volpicelli LA, Alterman AI, O'Brien CP. Naltrexone and alcohol dependence: role of subject compliance. Arch Gen Psychiatry 1997;54(8):737–742. DOI: 10.1001/archpsyc.1997.01830200071010. PMID: 9283509. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, How Long Does Naltrexone Take to Work?
Krupitsky E, Nunes EV, Ling W, Illeperuma A, Gastfriend DR, Silverman BL. Injectable extended-release naltrexone for opioid dependence: a double-blind, placebo-controlled, multicentre randomised trial. Lancet 2011;377(9776):1506–1513. DOI: 10.1016/S0140-6736(11)60358-9. PMID: 21529928. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Naltrexone: What It Is Used For and How It Works, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help
Krystal JH, Cramer JA, Krol WF, Kirk GF, Rosenheck RA; Veterans Affairs Naltrexone Cooperative Study 425 Group. Naltrexone in the treatment of alcohol dependence. N Engl J Med 2001;345(24):1734–1739. DOI: 10.1056/NEJMoa011127. PMID: 11742047. Accessed 2026-10-17.Cited on: Does Naltrexone Work?
Volpicelli JR, Alterman AI, Hayashida M, O'Brien CP. Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry 1992;49(11):876–880. DOI: 10.1001/archpsyc.1992.01820110040006. PMID: 1345133. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, How Long Does Naltrexone Take to Work?
O'Malley SS, Jaffe AJ, Chang G, Schottenfeld RS, Meyer RE, Rounsaville B. Naltrexone and coping skills therapy for alcohol dependence: a controlled study. Arch Gen Psychiatry 1992;49(11):881–887. DOI: 10.1001/archpsyc.1992.01820110045007. PMID: 1444726. Accessed 2026-10-17.Cited on: Does Naltrexone Work?
O'Malley SS, Krishnan-Sarin S, Farren C, Sinha R, Kreek MJ. Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis. Psychopharmacology (Berl) 2002;160(1):19–29. DOI: 10.1007/s002130100919. PMID: 11862370. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, How Long Does Naltrexone Take to Work?
Lee JD, Nunes EV, Novo P, et al. Comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone for opioid relapse prevention (X:BOT): a multicentre, open-label, randomised controlled trial. Lancet 2018;391(10118):309–318. DOI: 10.1016/S0140-6736(17)32812-X. PMID: 29150198. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Naltrexone vs Suboxone, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help
Bested K, Jensen LM, Andresen T, et al. Low-dose naltrexone for treatment of pain in patients with fibromyalgia: a randomized, double-blind, placebo-controlled, crossover study. Pain Rep 2023;8(4):e1080. DOI: 10.1097/PR9.0000000000001080. PMID: 38226027. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo
Due Bruun K, Christensen R, Amris K, et al. Naltrexone 6 mg once daily versus placebo in women with fibromyalgia: a randomised, double-blind, placebo-controlled trial. Lancet Rheumatol 2024;6(1):e31–e39. DOI: 10.1016/S2665-9913(23)00278-3. PMID: 38258677. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label
Rodríguez-Freire C, Navarrete J, Rozadilla-Sacanell A, et al. Efficacy of low-dose naltrexone in women with fibromyalgia syndrome: a 12-month randomised, double-blind, placebo-controlled single-centre clinical trial (INNOVA study). Eur J Pain 2026;30(6):e70321. DOI: 10.1002/ejp.70321. PMID: 42385209. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo
Tsui JI, Rossi SL, Cheng DM, et al. Pilot RCT comparing low-dose naltrexone, gabapentin and placebo to reduce pain among people with HIV with alcohol problems. PLoS One 2024;19(2):e0297948. DOI: 10.1371/journal.pone.0297948. PMID: 38408060. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, What to Avoid When Taking Low-Dose Naltrexone (LDN)
Younger J, Noor N, McCue R, Mackey S. Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels. Arthritis Rheum 2013;65(2):529–538. DOI: 10.1002/art.37734. PMID: 23359310. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Cree BA, Kornyeyeva E, Goodin DS. Pilot trial of low-dose naltrexone and quality of life in multiple sclerosis. Ann Neurol 2010;68(2):145–150. DOI: 10.1002/ana.22006. PMID: 20695007. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Srinivasan A, Dutta P, Bansal D, Chakrabarti A, Bhansali AK, Hota D. Efficacy and safety of low-dose naltrexone in painful diabetic neuropathy: a randomized, double-blind, active-control, crossover clinical trial. J Diabetes 2021;13(10):770–778. DOI: 10.1111/1753-0407.13202. PMID: 34014028. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Sharafaddinzadeh N, Moghtaderi A, Kashipazha D, Majdinasab N, Shalbafan B. The effect of low-dose naltrexone on quality of life of patients with multiple sclerosis: a randomized placebo-controlled trial. Mult Scler 2010;16(8):964–969. DOI: 10.1177/1352458510366857. PMID: 20534644. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Peters KB, Affronti ML, Woodring S, et al. Effects of low-dose naltrexone on quality of life in high-grade glioma patients: a placebo-controlled, double-blind randomized trial. Support Care Cancer 2022;30(4):3463–3471. DOI: 10.1007/s00520-021-06738-0. PMID: 35001215. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Doty P, Kirk JM, Cramblett MJ, de Wit H. Behavioral responses to ethanol in light and moderate social drinkers following naltrexone pretreatment. Drug Alcohol Depend 1997;47(2):109–116. DOI: 10.1016/s0376-8716(97)00094-x. PMID: 9298332. Accessed 2026-10-17.Cited on: Naltrexone and Alcohol: What Happens If You Drink on It
Swift RM, Whelihan W, Kuznetsov O, Buongiorno G, Hsuing H. Naltrexone-induced alterations in human ethanol intoxication. Am J Psychiatry 1994;151(10):1463–1467. DOI: 10.1176/ajp.151.10.1463. PMID: 8092339. Accessed 2026-10-17.Cited on: Naltrexone and Alcohol: What Happens If You Drink on It
Alla M, Varshney M, Bhardwaj A, Kumar G, Shasthry SM, Sarin SK. Naltrexone is superior to placebo for abstinence and craving reduction in alcohol-associated cirrhosis: NAL-CI trial. Liver Int 2026;46(9):e70845. DOI: 10.1111/liv.70845. PMID: 42615276. Accessed 2026-10-17.Cited on: Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone for Alcohol Use Disorder, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Lee JD, Friedmann PD, Kinlock TW, et al. Extended-release naltrexone to prevent opioid relapse in criminal justice offenders. N Engl J Med 2016;374(13):1232–1242. DOI: 10.1056/NEJMoa1505409. PMID: 27028913. Accessed 2026-10-17.Cited on: Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Hendershot CS, Bremmer MP, Paladino MB, et al. Once-weekly semaglutide in adults with alcohol use disorder: a randomized clinical trial. JAMA Psychiatry 2025;82(4):395-405. DOI: 10.1001/jamapsychiatry.2024.4789. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Johnson BA, Rosenthal N, Capece JA, et al. Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA 2007;298(14):1641-1651. DOI: 10.1001/jama.298.14.1641. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Mason BJ, Quello S, Goodell V, Shadan F, Kyle M, Begovic A. Gabapentin treatment for alcohol dependence: a randomized clinical trial. JAMA Intern Med 2014;174(1):70-77. DOI: 10.1001/jamainternmed.2013.11950. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Reynaud M, Aubin HJ, Trinquet F, et al. A randomized, placebo-controlled study of high-dose baclofen in alcohol-dependent patients: the ALPADIR study. Alcohol Alcohol 2017;52(4):439-446. DOI: 10.1093/alcalc/agx030. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
Mann K, Bladström A, Torup L, Gual A, van den Brink W. Extending the treatment options in alcohol dependence: a randomized controlled study of as-needed nalmefene. Biol Psychiatry 2013;73(8):706-713. DOI: 10.1016/j.biopsych.2012.10.020. Accessed 2026-10-17.Cited on: Nalmefene
Gual A, He Y, Torup L, van den Brink W, Mann K; ESENSE 2 Study Group. A randomised, double-blind, placebo-controlled, efficacy study of nalmefene, as-needed use, in patients with alcohol dependence. Eur Neuropsychopharmacol 2013;23(11):1432-1442. DOI: 10.1016/j.euroneuro.2013.02.006. Accessed 2026-10-17.Cited on: Nalmefene
Kaplan JL, Marx JA, Calabro JJ, et al. Double-blind, randomized study of nalmefene and naloxone in emergency department patients with suspected narcotic overdose. Ann Emerg Med 1999;34(1):42-50. DOI: 10.1016/s0196-0644(99)70270-2. Accessed 2026-10-17.Cited on: Nalmefene
Greenway FL, Dunayevich E, Tollefson G, et al. Comparison of combined bupropion and naltrexone therapy for obesity with monotherapy and placebo. J Clin Endocrinol Metab 2009;94(12):4898-4906. DOI: 10.1210/jc.2009-1350. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Grilo CM, Lydecker JA, Morgan PT, Gueorguieva R. Naltrexone + bupropion combination for the treatment of binge-eating disorder with obesity: a randomized, controlled pilot study. Clin Ther 2021;43(1):112-122.e1. DOI: 10.1016/j.clinthera.2020.10.010. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Trivedi MH, Walker R, Ling W, et al. Bupropion and naltrexone in methamphetamine use disorder. N Engl J Med 2021;384(2):140-153. DOI: 10.1056/NEJMoa2020214. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Greenway FL, Fujioka K, Plodkowski RA, et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2010;376(9741):595-605. DOI: 10.1016/S0140-6736(10)60888-4. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Wadden TA, Foreyt JP, Foster GD, et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring) 2011;19(1):110-120. DOI: 10.1038/oby.2010.147. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Hollander P, Gupta AK, Plodkowski R, et al. Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes. Diabetes Care 2013;36(12):4022-4029. DOI: 10.2337/dc13-0234. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Apovian CM, Aronne L, Rubino D, et al. A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity (Silver Spring) 2013;21(5):935-943. DOI: 10.1002/oby.20309. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Nissen SE, Wolski KE, Prcela L, et al. Effect of naltrexone-bupropion on major adverse cardiovascular events in overweight and obese patients with cardiovascular risk factors: a randomized clinical trial. JAMA 2016;315(10):990-1004. DOI: 10.1001/jama.2016.1558. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
Krupitsky E, Zvartau E, Blokhina E, et al. Randomized trial of long-acting sustained-release naltrexone implant vs oral naltrexone or placebo for preventing relapse to opioid dependence. Arch Gen Psychiatry 2012;69(9):973-981. DOI: 10.1001/archgenpsychiatry.2012.1a. Accessed 2026-10-17.Cited on: Naltrexone Implant
Hulse GK, Morris N, Arnold-Reed D, Tait RJ. Improving clinical outcomes in treating heroin dependence: randomized, controlled trial of oral or implant naltrexone. Arch Gen Psychiatry 2009;66(10):1108-1115. DOI: 10.1001/archgenpsychiatry.2009.130. Accessed 2026-10-17.Cited on: Naltrexone Implant
Krupitsky E, Blokhina E, Zvartau E, et al. Slow-release naltrexone implant versus oral naltrexone for improving treatment outcomes in people with HIV who are addicted to opioids: a double-blind, placebo-controlled, randomised trial. Lancet HIV 2019;6(4):e221-e229. DOI: 10.1016/S2352-3018(18)30362-X. Accessed 2026-10-17.Cited on: Naltrexone Implant
Petrakis IL, Poling J, Levinson C, et al; VA New England VISN I MIRECC Study Group. Naltrexone and disulfiram in patients with alcohol dependence and comorbid psychiatric disorders. Biol Psychiatry 2005;57(10):1128-1137. DOI: 10.1016/j.biopsych.2005.02.016. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse)
Fuller RK, Branchey L, Brightwell DR, et al. Disulfiram treatment of alcoholism: a Veterans Administration cooperative study. JAMA 1986;256(11):1449-1455. DOI: 10.1001/jama.1986.03380110055026. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse)
Pettinati HM, Kampman KM, Lynch KG, et al. A double blind, placebo-controlled trial that combines disulfiram and naltrexone for treating co-occurring cocaine and alcohol dependence. Addict Behav 2008;33(5):651-667. DOI: 10.1016/j.addbeh.2007.11.011. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse)
Tanum L, Solli KK, Latif ZE, et al. Effectiveness of injectable extended-release naltrexone vs daily buprenorphine-naloxone for opioid dependence: a randomized clinical noninferiority trial. JAMA Psychiatry 2017;74(12):1197-1205. DOI: 10.1001/jamapsychiatry.2017.3206. Accessed 2026-10-17.Cited on: Naltrexone vs Suboxone
Sullivan M, Bisaga A, Pavlicova M, et al. Long-acting injectable naltrexone induction: a randomized trial of outpatient opioid detoxification with naltrexone versus buprenorphine. Am J Psychiatry 2017;174(5):459-467. DOI: 10.1176/appi.ajp.2016.16050548. Accessed 2026-10-17.Cited on: Precipitated Withdrawal
Bisaga A, Mannelli P, Yu M, et al. Outpatient transition to extended-release injectable naltrexone for patients with opioid use disorder: a phase 3 randomized trial. Drug Alcohol Depend 2018;187:171-178. DOI: 10.1016/j.drugalcdep.2018.02.023. Accessed 2026-10-17.Cited on: Precipitated Withdrawal
Pettinati HM, Oslin DW, Kampman KM, et al. A double-blind, placebo-controlled trial combining sertraline and naltrexone for treating co-occurring depression and alcohol dependence. Am J Psychiatry 2010;167(6):668-675. DOI: 10.1176/appi.ajp.2009.08060852. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Adamson SJ, Sellman JD, Foulds JA, et al. A randomized trial of combined citalopram and naltrexone for nonabstinent outpatients with co-occurring alcohol dependence and major depression. J Clin Psychopharmacol 2015;35(2):143-149. DOI: 10.1097/JCP.0000000000000287. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Anton RF, Myrick H, Wright TM, et al. Gabapentin combined with naltrexone for the treatment of alcohol dependence. Am J Psychiatry 2011;168(7):709-717. DOI: 10.1176/appi.ajp.2011.10101436. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Haney M, Ramesh D, Glass A, Pavlicova M, Bedi G, Cooper ZD. Naltrexone maintenance decreases cannabis self-administration and subjective effects in daily cannabis smokers. Neuropsychopharmacology 2015;40(11):2489-2498. DOI: 10.1038/npp.2015.108. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone
Kunøe N, Lobmaier P, Vederhus JK, et al. Naltrexone implants after in-patient treatment for opioid dependence: randomised controlled trial. Br J Psychiatry 2009;194(6):541-546. DOI: 10.1192/bjp.bp.108.055319. Accessed 2026-10-17.Cited on: Naltrexone Implant
De Sousa A, De Sousa A. A one-year pragmatic trial of naltrexone vs disulfiram in the treatment of alcohol dependence. Alcohol Alcohol 2004;39(6):528-531. DOI: 10.1093/alcalc/agh104. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse)

Research study

Stewart MT, Feltus SR, Andrews CM, et al.. Alcohol Use Disorder Medication Coverage and Utilization Management in Medicaid Managed Care Plans. JAMA Network Open 2025;8(3):e250695. DOI: 10.1001/jamanetworkopen.2025.0695. PMID: 40080021. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
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Narrative review

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Guerzoni S, Pellesi L, Pini LA, Caputo F. Drug-drug interactions in the treatment for alcohol use disorders: a comprehensive review. Pharmacol Res 2018;133:65-76. DOI: 10.1016/j.phrs.2018.04.024. Accessed 2026-10-17.Cited on: What to Avoid When Taking Naltrexone

Government source

What is naltrexone? Side effects, uses, dose & risk. Substance Abuse and Mental Health Services Administration (SAMHSA), 2025. Accessed 2026-10-17.Cited on: Naltrexone: What It Is Used For and How It Works, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, What to Avoid When Taking Naltrexone
SAMHSA's National Helpline. Substance Abuse and Mental Health Services Administration (SAMHSA), n.d.. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Medication to Stop Drinking, Nalmefene, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone and Bupropion (Contrave), Naltrexone Brand Names, Naltrexone for Alcohol Use Disorder, Naltrexone Implant, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Can You Take Naltrexone While Pregnant?, Naltrexone vs Disulfiram (Antabuse), Naltrexone vs Suboxone, Precipitated Withdrawal
Alcohol withdrawal — MedlinePlus Medical Encyclopedia. U.S. National Library of Medicine (MedlinePlus), 2025. Accessed 2026-10-17.
21 CFR §1308.12 — Schedule II (eCFR, current as of October 1, 2026). National Archives and Records Administration (eCFR), 2026. Accessed 2026-10-17.Cited on: Is Naltrexone a Controlled Substance?, Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, Naltrexone: What It Is Used For and How It Works, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Naloxone: What's the Difference?, Naltrexone vs Suboxone, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Controlled substances – alphabetical order (dated August 27, 2026). U.S. Drug Enforcement Administration, Diversion Control Division, 2026. Accessed 2026-10-17.Cited on: Is Naltrexone a Controlled Substance?, Naltrexone: What It Is Used For and How It Works, Naltrexone and Bupropion (Contrave), Naltrexone Brand Names, Naltrexone vs Naloxone: What's the Difference?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
FDA approves first over-the-counter naloxone nasal spray. U.S. Food and Drug Administration, 2023. Accessed 2026-10-17.Cited on: Is Naltrexone a Controlled Substance?, Naltrexone: What It Is Used For and How It Works, Naltrexone vs Naloxone: What's the Difference?
Compounding and the FDA: questions and answers. U.S. Food and Drug Administration, 2025. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, Naltrexone: What It Is Used For and How It Works, Naltrexone Brand Names, Naltrexone Implant, Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
NDC directory record: product NDC 69238-2794 (naltrexone kit). U.S. Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?
Drugs@FDA application records for naltrexone products. U.S. Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse), Naltrexone vs Vivitrol: Pill or Monthly Shot?, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Alkermes plc, Form 8-K: termination of a material definitive agreement (event date July 6, 2026). U.S. Securities and Exchange Commission (EDGAR), 2026. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?
42 CFR Part 447 — Payments for services (§§447.53, 447.502, 447.512; eCFR, current as of October 1, 2026). National Archives and Records Administration (eCFR), 2026. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?
NADAC (National Average Drug Acquisition Cost) 2026. Centers for Medicare & Medicaid Services (data.medicaid.gov), 2026. Accessed 2026-10-17.Note: What pharmacies pay to buy a drug, on average. Not what patients pay.Cited on: How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
NADAC data dictionary. Centers for Medicare & Medicaid Services (data.medicaid.gov), n.d.. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?
October 2026 Medicare Part B payment limit file (effective October 1 – December 31, 2026). Centers for Medicare & Medicaid Services, 2026. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
October 2026 ASP NDC-HCPCS crosswalk. Centers for Medicare & Medicaid Services, 2026. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?
2026 Medicare Parts A & B premiums and deductibles (fact sheet). Centers for Medicare & Medicaid Services, 2025. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?
Medicare costs. Medicare.gov (Centers for Medicare & Medicaid Services), n.d.. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?
How much does Medicare drug coverage cost?. Medicare.gov (Centers for Medicare & Medicaid Services), n.d.. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?
Opioid use disorder treatment services. Medicare.gov (Centers for Medicare & Medicaid Services), n.d.. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Mental health & substance use disorders. Medicare.gov (Centers for Medicare & Medicaid Services), n.d.. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?
Medicaid coverage of medications to reverse opioid overdose and treat alcohol and opioid use disorders (HHS Publication No. PEP22-06-01-009). Substance Abuse and Mental Health Services Administration (SAMHSA), 2024. Accessed 2026-10-17.Note: Coverage data are from 2023.Cited on: Medication to Stop Drinking, How Much Does Naltrexone Cost?, Naltrexone vs Acamprosate: Which Works Better?, Naltrexone vs Disulfiram (Antabuse), Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Recommend evidence-based treatment: know the options. National Institute on Alcohol Abuse and Alcoholism, 2025. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone and Bupropion (Contrave), Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Disulfiram (Antabuse)
Alcohol treatment in the United States: age groups and demographic characteristics. National Institute on Alcohol Abuse and Alcoholism, 2026. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone for Alcohol Use Disorder
Revia (naltrexone HCl) tablets: detailed view: safety labeling changes approved by FDA Center for Drug Evaluation and Research (CDER). US Food and Drug Administration (Internet Archive capture), 2013. Accessed 2026-10-17.Note: Archived copy (Internet Archive).Cited on: Does Naltrexone Work?, Naltrexone: What It Is Used For and How It Works, Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, What to Avoid When Taking Naltrexone
Mandatory Guidelines for Federal Workplace Drug Testing Programs—Authorized Testing Panels. Federal Register (Substance Abuse and Mental Health Services Administration), 2026. Accessed 2026-10-17.Cited on: How Long Does Naltrexone Stay in Your System?
Naltrexone. MedlinePlus, US National Library of Medicine, 2026. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, How Long Does Naltrexone Take to Work?, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor
FDA approves second over-the-counter naloxone nasal spray product. US Food and Drug Administration, 2023. Accessed 2026-10-17.Cited on: Is Naltrexone a Controlled Substance?, Naltrexone vs Naloxone: What's the Difference?
NDC directory: generic name naltrexone. US Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects, LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo, Naltrexone: What It Is Used For and How It Works, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, What to Avoid When Taking Low-Dose Naltrexone (LDN)
Drugs@FDA: naltrexone (ANDA 076264, SpecGx LLC; and other naltrexone applications). openFDA, US Food and Drug Administration. US Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label
Understanding alcohol use disorder. National Institute on Alcohol Abuse and Alcoholism, 2025. Accessed 2026-10-17.Cited on: Naltrexone: What It Is Used For and How It Works, Naltrexone for Alcohol Use Disorder
Neuroscience: the brain in addiction and recovery. National Institute on Alcohol Abuse and Alcoholism, n.d.. Accessed 2026-10-17.Cited on: Naltrexone for Alcohol Use Disorder
Alcohol use disorder (AUD) in the United States: age groups and demographic characteristics. National Institute on Alcohol Abuse and Alcoholism, 2025. Accessed 2026-10-17.Cited on: Naltrexone for Alcohol Use Disorder
Opioid overdose reversal medications (OORM). Substance Abuse and Mental Health Services Administration, 2025. Accessed 2026-10-17.Cited on: Naltrexone vs Naloxone: What's the Difference?
Drugs@FDA: products with active ingredient naltrexone (openFDA drugsfda endpoint query). US Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
NDC directory search: products containing both naltrexone and pyridoxine (openFDA drug/ndc endpoint query; result: no matches). US Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
FindTreatment.gov. Substance Abuse and Mental Health Services Administration, n.d.. Accessed 2026-10-17.Cited on: Medication to Stop Drinking, Can You Take Naltrexone While Pregnant?, Naltrexone vs Suboxone, Precipitated Withdrawal, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Exemptions and consideration for certain drugs, devices, and biological products, 21 USC §353(b)(1). Legal Information Institute, Cornell Law School, n.d.. Accessed 2026-10-17.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Prescriptions, 21 USC §829(e). Legal Information Institute, Cornell Law School, n.d.. Accessed 2026-10-17.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Drugs@FDA application records for naltrexone products. US Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: Naltrexone: What It Is Used For and How It Works, Naltrexone Brand Names, Where to Get Naltrexone Online: Prescribers, Programs and Prices
FDA to telehealth companies: what to know when promoting compounded drugs. US Food and Drug Administration, 2026. Accessed 2026-10-17.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
BeSafeRx: considering an online pharmacy?. US Food and Drug Administration, 2020. Accessed 2026-10-17.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
BeSafeRx: locate a state-licensed online pharmacy. US Food and Drug Administration, n.d.. Accessed 2026-10-17.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Selincro (nalmefene): EPAR summary for the public. European Medicines Agency, 2025. Accessed 2026-10-17.Cited on: Medication to Stop Drinking, Nalmefene
Drugs@FDA: nalmefene hydrochloride applications (NDA 020459, NDA 217470, NDA 218590, ANDA 212955, ANDA 216007). US Food and Drug Administration (openFDA), 2026. Accessed 2026-10-17.Cited on: Medication to Stop Drinking, Nalmefene
NIAAA Alcohol Treatment Navigator. National Institute on Alcohol Abuse and Alcoholism (NIAAA), n.d.. Accessed 2026-10-17.Cited on: Medication to Stop Drinking
FDA approves prescription nasal spray to reverse opioid overdose. US Food and Drug Administration, 2023. Accessed 2026-10-17.Cited on: Nalmefene
Drugs@FDA application records for naltrexone and bupropion products (NDA 200063 and ANDA 208043). US Food and Drug Administration (openFDA), 2026. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave)
NDC directory: finished products with generic name naltrexone. US Food and Drug Administration (openFDA), 2026. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
RxNorm concept history and historical NDCs for Depade (naltrexone hydrochloride) 25 mg, 50 mg and 100 mg oral tablets (RXCUI 1483782, 1483767 and 1483776). RxNav (US National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
Approved Drug Products With Therapeutic Equivalence Evaluations (Orange Book): data files. US Food and Drug Administration, 2026. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
DEPADE. US Patent and Trademark Office, n.d.. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
Drugs@FDA: FDA-approved drugs. US Food and Drug Administration, 2026. Accessed 2026-10-17.Cited on: Naltrexone Implant
Safety and PK study of BICX104 with or without bupropion compared to Vivitrol. ClinicalTrials.gov (US National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Naltrexone Implant
iSTEP-N 101b: pharmacokinetics and safety study of low- and high-dose naltrexone implants vs monthly Vivitrol in healthy volunteers. ClinicalTrials.gov (US National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Naltrexone Implant
Phase II clinical study on the efficacy and safety of naltrexone implant in patients with alcohol use disorder. ClinicalTrials.gov (US National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Naltrexone Implant
Evaluate the efficacy and safety of naltrexone hydrochloride implant in patients with alcohol use disorder. ClinicalTrials.gov (US National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Naltrexone Implant
Evaluation of the O'Neil Long Acting Naltrexone Implant in opioid dependent persons. ClinicalTrials.gov (US National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Naltrexone Implant
The O'Neil Long Acting Naltrexone Implant (OLANI) pharmacokinetic (PK)/safety study in healthy volunteers. ClinicalTrials.gov (US National Library of Medicine), 2024. Accessed 2026-10-17.Cited on: Naltrexone Implant
Pharmacokinetic and safety study of naltrexone release from subcutaneous BICX104 pellets compared to Vivitrol injections. ClinicalTrials.gov (US National Library of Medicine), 2023. Accessed 2026-10-17.Cited on: Naltrexone Implant
Study of the BIOPIN 6 naltrexone implant in healthy adults. ClinicalTrials.gov (US National Library of Medicine), 2026. Accessed 2026-10-17.Cited on: Naltrexone Implant
ALT blood test. MedlinePlus (US National Library of Medicine), 2024. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
AST test. MedlinePlus (US National Library of Medicine), 2024. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Gamma-glutamyl transferase (GGT) test. MedlinePlus (US National Library of Medicine), 2024. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Treatment of opioid use disorder before, during, and after pregnancy. Centers for Disease Control and Prevention (CDC), 2026. Accessed 2026-10-17.Cited on: Can You Take Naltrexone While Pregnant?
Treating opioid dependence during breastfeeding. NHS Specialist Pharmacy Service, 2023. Accessed 2026-10-17.Cited on: Can You Take Naltrexone While Pregnant?
Pregnancy and lactation labeling resources. US Food and Drug Administration, 2025. Accessed 2026-10-17.Cited on: Can You Take Naltrexone While Pregnant?
Drugs@FDA application records for disulfiram products (including NDA 007883, ANDA 091563, ANDA 091619 and ANDA 091681). US Food and Drug Administration (openFDA), n.d.. Accessed 2026-10-17.Cited on: Naltrexone vs Disulfiram (Antabuse)
Eosinophil count - absolute. MedlinePlus (US National Library of Medicine), 2025. Accessed 2026-10-17.Cited on: Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help
FDA and kratom. US Food and Drug Administration, 2025. Accessed 2026-10-17.Cited on: What to Avoid When Taking Low-Dose Naltrexone (LDN), What to Avoid When Taking Naltrexone
Determination that REVIA (naltrexone hydrochloride) tablets, 50 milligrams was not withdrawn from sale for reasons of safety or effectiveness. Federal Register (Office of the Federal Register), 2026. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
Teva Women's Health, Inc., et al.; withdrawal of approval of 16 new drug applications. Federal Register (Office of the Federal Register), 2019. Accessed 2026-10-17.Cited on: Naltrexone Brand Names
Content and format of labeling for human prescription drug and biological products; requirements for pregnancy and lactation labeling. Federal Register (Office of the Federal Register), 2014. Accessed 2026-10-17.Cited on: Can You Take Naltrexone While Pregnant?
About DailyMed. DailyMed (U.S. National Library of Medicine), n.d.. Accessed 2026-10-17.Cited on: Naltrexone Implant
Naltrexone (LiverTox). National Institute of Diabetes and Digestive and Kidney Diseases, via NCBI Bookshelf, 2020. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
ANDA 208043 tentative approval letter to Actavis Laboratories FL, Inc. (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets, 8 mg/90 mg). US Food and Drug Administration, Office of Generic Drugs, 2022. Accessed 2026-10-17.Cited on: Naltrexone and Bupropion (Contrave), Naltrexone Brand Names
Supplement approval letter to Alkermes, Inc., NDA 021897/S-020, S-023 (Vivitrol). US Food and Drug Administration, 2013. Accessed 2026-10-17.Cited on: Naltrexone and Your Liver: What Liver Tests Show at the Usual Dose
Results From the 2024 National Survey on Drug Use and Health: Detailed Tables, Table 5.21B (received medications for alcohol use disorder in the past year). Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Behavioral Health Statistics and Quality, 2025. Accessed 2026-10-17.Cited on: Does Naltrexone Work?, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone for Alcohol Use Disorder, Naltrexone vs Acamprosate: Which Works Better?
National Institute on Alcohol Abuse and Alcoholism. Alcohol Use Disorder: A Comparison Between DSM–IV and DSM–5. National Institute on Alcohol Abuse and Alcoholism, 2021. Accessed 2026-10-17.
National Institute on Alcohol Abuse and Alcoholism. What Is A Standard Drink?. National Institute on Alcohol Abuse and Alcoholism, n.d.. Accessed 2026-10-17.

Nonprofit organization

988 Suicide & Crisis Lifeline. 988 Suicide & Crisis Lifeline, n.d.. Accessed 2026-10-17.Cited on: Does Naltrexone Make You Sleepy or Tired?, Medication to Stop Drinking, Naltrexone: What It Is Used For and How It Works, Naltrexone and Alcohol: What Happens If You Drink on It, Naltrexone Dosage: Label Doses for Alcohol, Opioids and Vivitrol, and What's Off-Label, Naltrexone for Alcohol Use Disorder, Can You Take Naltrexone While Pregnant?, Naltrexone Side Effects: How Common Each One Is and When to Call a Doctor, Naltrexone vs Suboxone, Precipitated Withdrawal, Vivitrol Side Effects: Trial Rates, Injection-Site Reactions and When to Get Help
Oar Health, Inc. complaints. Better Business Bureau, n.d.. Accessed 2026-10-17.Note: Third-party listing; figures as displayed on the access date.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
Oar Health, Inc. business profile. Better Business Bureau Serving Metropolitan New York, n.d.. Accessed 2026-10-17.Note: Third-party listing; figures as displayed on the access date.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
Oar Health, Inc. customer reviews. Better Business Bureau, n.d.. Accessed 2026-10-17.Note: Third-party listing; figures as displayed on the access date.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
University of Utah Health names CEO of Huntsman Mental Health Institute and new chair of the Department of Psychiatry. University of Utah Health, 2020. Accessed 2026-10-17.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Are there withdrawal symptoms from LDN?. LDN Research Trust, n.d.. Accessed 2026-10-17.Cited on: LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo
Is there a time you should quit low dose naltrexone (LDN)?. LDN Research Trust, n.d.. Accessed 2026-10-17.Cited on: LDN Side Effects: What Low-Dose Naltrexone Trials Found Compared With Placebo
Poison Control. National Capital Poison Center, n.d.. Accessed 2026-10-17.Cited on: Nalmefene, Precipitated Withdrawal

Commercial source

VIVITROL Co-pay Savings Program (alcohol dependence). Alkermes, Inc. (manufacturer of Vivitrol), n.d.. Accessed 2026-10-17.Note: Manufacturer's promotional page; program terms can change.Cited on: How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Naltrexone HCl 50mg tablet. Mark Cuban Cost Plus Drug Company, PBC, n.d.. Accessed 2026-10-17.Note: The seller's own price; prescription required; shipping and taxes extra.
Naltrexone prices, coupons, copay cards & patient assistance. Drugs.com, n.d.. Accessed 2026-10-17.Note: Discount-card cash prices; not valid with insurance; prices change.Cited on: How Much Does Naltrexone Cost?
Vivitrol prices, coupons, copay cards & patient assistance. Drugs.com, n.d.. Accessed 2026-10-17.Note: Discount-card cash prices; not valid with insurance; prices change.Cited on: Naltrexone: What It Is Used For and How It Works, How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Alcoholism as a problem? Humane treatment method. Contral Clinics, n.d.. Accessed 2026-10-17.Note: Finnish clinic chain that offers the method; promotional source.Cited on: The Sinclair Method: What It Is and What the Evidence Shows
Brindley M. The Sinclair Method success rate: what the research shows. Rethink Drink, 2026. Accessed 2026-10-17.Note: Commercial service that offers the method; cited only for how it describes the 78% figure.Cited on: The Sinclair Method: What It Is and What the Evidence Shows
Alcohol treatment. Workit Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Naltrexone vs Vivitrol: Pill or Monthly Shot?, Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Alcohol addiction treatment. Rezolv Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
FAQs. Boulder Care, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Naltrexone online prescription. Oar Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Naltrexone vs Vivitrol: Pill or Monthly Shot?, Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Naltrexone. Talkspace Psychiatry, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Oar Health FAQs: naltrexone online. Oar Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Reframe Med+. Reframe, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Naltrexone for Alcohol Use Disorder, Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Sunnyside Med: naltrexone + a personal plan. Sunnyside, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Naltrexone for Alcohol Use Disorder, Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
How it works. Sunnyside, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
About us, our mission and the team. Sunnyside, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Online alcohol addiction program FAQs. Ria Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, The Sinclair Method: What It Is and What the Evidence Shows, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Naltrexone for alcohol use disorder: uses & safety. Ria Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Insurance coverage for online alcohol rehab. Ria Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Medication for alcohol treatment: how it works. Ria Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Online alcohol treatment locations. Ria Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Evaluation of opiate results. Sullivan Nicolaides Pathology, 2020. Accessed 2026-10-17.Note: Pathology laboratory's interpretive protocol (Australia).Cited on: How Long Does Naltrexone Stay in Your System?
LDN (low dose naltrexone). AgelessRx, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Low dose naltrexone (LDN). HealthHub, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Low dose naltrexone (LDN). AgelessRx, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Low-dose naltrexone (LDN) capsules. MintRx Pharmacy, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Low dose naltrexone (LDN). Everlife, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Low-dose naltrexone (LDN) online prescription. Wisp, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Low dose naltrexone. Hone Health, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
Hone Health: low dose naltrexone (LDN) capsule. Hone Health Help Center, n.d.. Accessed 2026-10-17.Note: Seller's own page; advertised price, not checked at checkout.Cited on: Low-Dose Naltrexone (LDN): Off-Label Doses, Evidence by Condition and Side Effects
A daily pill to drink less or quit. Oar Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Automatically renewing subscription terms. Oar Health, 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
Terms and conditions of use. Oar Health, 2023. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
Oarhealth reviews. Trustpilot, n.d.. Accessed 2026-10-17.Note: Third-party review site; individual reviews are unverified.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
Our clinicians. Oar Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
Kopp D. Oar Health reviews: alcohol moderation success stories. Oar Health, 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time
Dion K. How to start Clutch: the fast-acting naltrexone mint. Oar Health, 2026. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, The Sinclair Method: What It Is and What the Evidence Shows
Insurance and pricing. Workit Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Reframe: Drink Less & Thrive. Apple Inc. (App Store), n.d.. Accessed 2026-10-17.Note: Third-party app-store listing; figures as displayed on the access date.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
FAQ. Reframe, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Sunnyside: alcohol habit change app. Sunnyside, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Sunnyside - Naltrexone & App to Drink Less or Quit: 1-star reviews and company replies. Trustpilot, n.d.. Accessed 2026-10-17.Note: Third-party review site; individual reviews are unverified.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Get access to online alcohol treatment (landing page; riahealth.com/optum/ redirects here). Ria Health, Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Ria Health terms of use. Ria Technology Management Inc., 2023. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Locations. Workit Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Oar Health Reviews: A Prescription by Message, Paid Three Months at a Time, Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree, Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price, Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Reframe: Cut Back on Alcohol. Google LLC (Google Play), n.d.. Accessed 2026-10-17.Note: Third-party app-store listing; figures as displayed on the access date.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
How much does Reframe App cost and what are the subscription options?. Glucobit Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Terms of service. Reframe, 2023. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Terms and conditions of services. Reframe Med+, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Reframe: Drink Less & Thrive reviews. Trustpilot, n.d.. Accessed 2026-10-17.Note: Third-party review site; individual reviews are unverified.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Reframe: drink less, live more. Glucobit Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
About. Reframe, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
About | Reframe App. Internet Archive (capture of joinreframeapp.com), 2021. Accessed 2026-10-17.Note: Archived copy of the provider's page (Internet Archive).Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
About | Reframe App. Internet Archive (capture of joinreframeapp.com), 2023. Accessed 2026-10-17.Note: Archived copy of the provider's page (Internet Archive).Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
About | Reframe App. Internet Archive (capture of joinreframeapp.com), 2025. Accessed 2026-10-17.Note: Archived copy of the provider's page (Internet Archive).Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Liquid Luck functional elixir. Reframe, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Reframe reviews. Glucobit Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Telehealth consent form. Reframe Med+ / OpenLoop Healthcare Partners, PC, 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Reframe App Reviews: A Well-Rated App Whose Own Documents Disagree
Ria Health: 1-star reviews and company replies. Trustpilot, n.d.. Accessed 2026-10-17.Note: Third-party review site; individual reviews are unverified.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Physician consultation. Ria Health, Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Our team. Ria Health, Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
About Ria Health. Ria Health, Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Alcohol withdrawal: what to expect when you stop drinking. Ria Health, Inc., 2022. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Recovery coaching. Ria Health, Inc., 2022. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Ria Health reviews. Trustpilot, n.d.. Accessed 2026-10-17.Note: Third-party review site; individual reviews are unverified.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Ria Health. Apple Inc. (App Store), n.d.. Accessed 2026-10-17.Note: Third-party app-store listing; figures as displayed on the access date.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Ria Health. Google LLC (Google Play), n.d.. Accessed 2026-10-17.Note: Third-party app-store listing; figures as displayed on the access date.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Ria Health (former App Store listing, id 1084040297; page returned an error and the iTunes Search API returned no result on the access date). Apple Inc. (App Store), n.d.. Accessed 2026-10-17.Note: Third-party app-store listing; figures as displayed on the access date.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Medications for alcohol use disorder. Ria Health, Inc., 2024. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Research. Ria Health, Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Accreditations. Ria Health, Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Privacy policy. Ria Health, Inc., 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Confidentiality. Ria Health, Inc., n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Ria Health Reviews: Insurance-Billed Alcohol Treatment With No Posted Price
Terms and conditions of service. Sunnyside, 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Telehealth consent form. OpenLoop Healthcare Partners, PC (posted by Sunnyside), 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Sunnyside: Drink Less Alcohol. Apple Inc. (App Store), n.d.. Accessed 2026-10-17.Note: Third-party app-store listing; figures as displayed on the access date.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Sunnyside: Cut Back or Quit Drinking. Google LLC (Google Play), n.d.. Accessed 2026-10-17.Note: Third-party app-store listing; figures as displayed on the access date.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Sunnyside - Naltrexone & App to Drink Less or Quit reviews. Trustpilot, n.d.. Accessed 2026-10-17.Note: Third-party review site; individual reviews are unverified.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Andersen I. New research reveals that Sunnyside's adaptive approach can decrease alcohol consumption by 33% in 12 weeks. Sunnyside blog, 2026. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Results. Sunnyside, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Privacy policy. Sunnyside, 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Consumer health data privacy policy. Sunnyside, 2025. Accessed 2026-10-17.Note: Provider's own page.Cited on: Sunnyside Reviews: A Drink-Less App Not Meant for Alcohol Use Disorder
Understanding the prescription process. Alkermes, Inc., n.d.. Accessed 2026-10-17.Note: Manufacturer's page.Cited on: Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Find a VIVITROL provider near you. Alkermes, Inc., n.d.. Accessed 2026-10-17.Note: Manufacturer's page.Cited on: Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Online alcohol treatment program with naltrexone. Choose Your Horizon, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: How Much Does Naltrexone Cost?, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Naltrexone. Sunflower Clinic, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: How Much Does Naltrexone Cost?, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Peer Support Groups. Sunflower, n.d.. Accessed 2026-10-18.Note: Provider's own page (the Sunflower app).
Features. Sunflower, n.d.. Accessed 2026-10-18.Note: Provider's own page (the Sunflower app).
Sunflower - Quit Any Addiction. Apple App Store (US), n.d.. Accessed 2026-10-18.Note: App listing; the description is written by the app's seller.
Sunflower: We are building an AI-native telemedicine clinic for addiction. Y Combinator, n.d.. Accessed 2026-10-18.Note: Company profile written by Sunflower; figures are the company's own.
California. Rezolv Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: How Much Does Naltrexone Cost?, Where to Get Naltrexone Online: Prescribers, Programs and Prices
Alcohol use care. EnnHealth Psychiatry, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Eligibility and insurance. Boulder Care, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Payment and insurance. Eleanor Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
FAQs. FirePit Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Terms of use. Choose Your Horizon, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Eleanor Health. Eleanor Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Pricing. Talkspace, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Prescribed medications. Eleanor Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Insurance. EnnHealth Psychiatry, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Online naltrexone treatment. FirePit Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Sunflower Clinic. Sunflower Limited, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Locations. Sunflower Clinic, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Medication-assisted treatment. Confidant Health, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
FAQ. Monument, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
Naltrexone for weight management. Nurx, n.d.. Accessed 2026-10-17.Note: Provider's own page.Cited on: Where to Get Naltrexone Online: Prescribers, Programs and Prices
VIVITROL co-pay savings program terms and conditions. Alkermes, Inc., n.d.. Accessed 2026-10-17.Cited on: How Much Does Naltrexone Cost?, Naltrexone vs Vivitrol: Pill or Monthly Shot?, Vivitrol: The Monthly Naltrexone Shot for Alcohol and Opioid Use Disorder
Naltrexone implants. Aetna, 2025. Accessed 2026-10-17.Cited on: Naltrexone Implant
Naltrexone implant. Complete Pharmacy and Medical Solutions, via DailyMed (U.S. National Library of Medicine), 2018. Accessed 2026-10-17.Cited on: Naltrexone Implant